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Cefiderocol Protects against Cytokine- and Endotoxin-Induced Disruption of Vascular Endothelial Cell Integrity in an In Vitro Experimental Model

The severe course of bloodstream infections with Gram-negative bacilli can lead to organ dysfunctions and compromise the integrity of the vascular barrier, which are the hallmarks of sepsis. This study aimed to investigate the potential effect of cefiderocol on the barrier function of vascular endot...

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Detalles Bibliográficos
Autores principales: Hildebrand, Dagmar, Böhringer, Jana, Körner, Eva, Chiriac, Ute, Förmer, Sandra, Sähr, Aline, Hoppe-Tichy, Torsten, Heeg, Klaus, Nurjadi, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137736/
https://www.ncbi.nlm.nih.gov/pubmed/35625225
http://dx.doi.org/10.3390/antibiotics11050581