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Identification of Modulators of the C. elegans Aryl Hydrocarbon Receptor and Characterization of Transcriptomic and Metabolic AhR-1 Profiles

The Aryl hydrocarbon Receptor (AhR) is a xenobiotic sensor in vertebrates, regulating the metabolism of its own ligands. However, no ligand has been identified to date for any AhR in invertebrates. In C. elegans, the AhR ortholog, AHR-1, displays physiological functions. Therefore, we compared the t...

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Detalles Bibliográficos
Autores principales: Larigot, Lucie, Bui, Linh-Chi, de Bouvier, Marine, Pierre, Ophélie, Pinon, Grégory, Fiocca, Justine, Ozeir, Mohammad, Tourette, Cendrine, Ottolenghi, Chris, Imbeaud, Sandrine, Pontoizeau, Clément, Blaise, Benjamin J., Chevallier, Aline, Tomkiewicz, Céline, Legrand, Béatrice, Elena-Herrmann, Bénédicte, Néri, Christian, Brinkmann, Vanessa, Nioche, Pierre, Barouki, Robert, Ventura, Natascia, Dairou, Julien, Coumoul, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137885/
https://www.ncbi.nlm.nih.gov/pubmed/35624894
http://dx.doi.org/10.3390/antiox11051030