Caudal–Rostral Progression of Alpha Motoneuron Degeneration in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

Mice with transgenic expression of human SOD1(G93A) are a widely used model of ALS, with a caudal–rostral progression of motor impairment. Previous studies have quantified the progression of motoneuron (MN) degeneration based on size, even though alpha (α-) and gamma (γ-) MNs overlap in size. Theref...

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Detalles Bibliográficos
Autores principales: Kirby, Alastair J., Palmer, Thomas, Mead, Richard J., Ichiyama, Ronaldo M., Chakrabarty, Samit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137889/
https://www.ncbi.nlm.nih.gov/pubmed/35624847
http://dx.doi.org/10.3390/antiox11050983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137889/
https://www.ncbi.nlm.nih.gov/pubmed/35624847
http://dx.doi.org/10.3390/antiox11050983

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