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Substance P Hinders Bile Acid-Induced Hepatocellular Injury by Modulating Oxidative Stress and Inflammation

Liver failure is an outcome of chronic liver disease caused by steatohepatitis and cholestatic injury. This study examined substance P (SP) effect on liver injury due to cholestatic stress caused by excessive bile acid (BA) accumulation. Chenodeoxycholic acid (CDCA) was added to HepG2 cells to induc...

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Detalles Bibliográficos
Autores principales: Lee, Dahyeon, Park, Jeong Seop, Kim, Doyoung, Hong, Hyun Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137937/
https://www.ncbi.nlm.nih.gov/pubmed/35624784
http://dx.doi.org/10.3390/antiox11050920