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Glycolaldehyde, an Advanced Glycation End Products Precursor, Induces Apoptosis via ROS-Mediated Mitochondrial Dysfunction in Renal Mesangial Cells

Glycolaldehyde (GA) is a reducing sugar and a precursor of advanced glycation end products (AGEs). The role of precursor and precursor-derived AGEs in diabetes and its complications have been actively discussed in the literature. This study aimed to elucidate the mechanism of GA-induced apoptosis in...

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Detalles Bibliográficos
Autores principales: Gu, Min Ji, Hyon, Ju-Youg, Lee, Hee-Weon, Han, Eun Hee, Kim, Yoonsook, Cha, Youn-Soo, Ha, Sang Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137959/
https://www.ncbi.nlm.nih.gov/pubmed/35624799
http://dx.doi.org/10.3390/antiox11050934