Study on the Neuroprotective, Radical-Scavenging and MAO-B Inhibiting Properties of New Benzimidazole Arylhydrazones as Potential Multi-Target Drugs for the Treatment of Parkinson’s Disease

Oxidative stress is a key contributing factor in the complex degenerating cascade in Parkinson’s disease. The inhibition of MAO-B affords higher dopamine bioavailability and stops ROS formation. The incorporation of hydroxy and methoxy groups in the arylhydrazone moiety of a new series of 1,3-disubs...

Descripción completa

Detalles Bibliográficos
Autores principales: Anastassova, Neda, Aluani, Denitsa, Hristova-Avakumova, Nadya, Tzankova, Virginia, Kondeva-Burdina, Magdalena, Rangelov, Miroslav, Todorova, Nadezhda, Yancheva, Denitsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138090/
https://www.ncbi.nlm.nih.gov/pubmed/35624746
http://dx.doi.org/10.3390/antiox11050884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138090/
https://www.ncbi.nlm.nih.gov/pubmed/35624746
http://dx.doi.org/10.3390/antiox11050884

Ejemplares similares