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Study on the Neuroprotective, Radical-Scavenging and MAO-B Inhibiting Properties of New Benzimidazole Arylhydrazones as Potential Multi-Target Drugs for the Treatment of Parkinson’s Disease

Oxidative stress is a key contributing factor in the complex degenerating cascade in Parkinson’s disease. The inhibition of MAO-B affords higher dopamine bioavailability and stops ROS formation. The incorporation of hydroxy and methoxy groups in the arylhydrazone moiety of a new series of 1,3-disubs...

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Detalles Bibliográficos
Autores principales:	Anastassova, Neda, Aluani, Denitsa, Hristova-Avakumova, Nadya, Tzankova, Virginia, Kondeva-Burdina, Magdalena, Rangelov, Miroslav, Todorova, Nadezhda, Yancheva, Denitsa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138090/ https://www.ncbi.nlm.nih.gov/pubmed/35624746 http://dx.doi.org/10.3390/antiox11050884

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