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Computational Design of Inhibitors Targeting the Catalytic β Subunit of Escherichia coli F(O)F(1)-ATP Synthase
With the uncontrolled growth of multidrug-resistant bacteria, there is an urgent need to search for new therapeutic targets, to develop drugs with novel modes of bactericidal action. FoF1-ATP synthase plays a crucial role in bacterial bioenergetic processes, and it has emerged as an attractive antim...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138118/ https://www.ncbi.nlm.nih.gov/pubmed/35625201 http://dx.doi.org/10.3390/antibiotics11050557 |