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Comparison of Piperacillin and Tazobactam Pharmacokinetics in Critically Ill Patients with Trauma or with Burn

Critical illness caused by burn and sepsis is associated with pathophysiologic changes that may result in the alteration of pharmacokinetics (PK) of antibiotics. However, it is unclear if one mechanism of critical illness alters PK more significantly than another. We developed a population PK model...

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Detalles Bibliográficos
Autores principales: Selig, Daniel J., Akers, Kevin S., Chung, Kevin K., Kress, Adrian T., Livezey, Jeffrey R., Por, Elaine D., Pruskowski, Kaitlin A., DeLuca, Jesse P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138153/
https://www.ncbi.nlm.nih.gov/pubmed/35625262
http://dx.doi.org/10.3390/antibiotics11050618