Cerebrospinal Fluid Neurofilament Light Predicts Risk of Dementia Onset in Cognitively Healthy Individuals and Rate of Cognitive Decline in Mild Cognitive Impairment: A Prospective Longitudinal Study

Background: Biomarkers that are indicative of early biochemical aberrations are needed to predict the risk of dementia onset and progression in Alzheimer’s disease (AD). We assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL) chain for screening preclinical AD, predicting deme...

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Detalles Bibliográficos
Autores principales: Dhiman, Kunal, Villemagne, Victor L., Fowler, Christopher, Bourgeat, Pierrick, Li, Qiao-Xin, Collins, Steven, Bush, Ashley I., Rowe, Christopher C., Masters, Colin L., Ames, David, Blennow, Kaj, Zetterberg, Henrik, Martins, Ralph N., Gupta, Veer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138299/
https://www.ncbi.nlm.nih.gov/pubmed/35625782
http://dx.doi.org/10.3390/biomedicines10051045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138299/
https://www.ncbi.nlm.nih.gov/pubmed/35625782
http://dx.doi.org/10.3390/biomedicines10051045

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