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Comparative Analysis of the Relative Fragmentation Stabilities of Polymorphic Alpha-Synuclein Amyloid Fibrils

The division of amyloid fibril particles through fragmentation is implicated in the progression of human neurodegenerative disorders such as Parkinson’s disease. Fragmentation of amyloid fibrils plays a crucial role in the propagation of the amyloid state encoded in their three-dimensional structure...

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Detalles Bibliográficos
Autores principales: Sanami, Sarina, Purton, Tracey J., Smith, David P., Tuite, Mick F., Xue, Wei-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138312/
https://www.ncbi.nlm.nih.gov/pubmed/35625557
http://dx.doi.org/10.3390/biom12050630