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Heterologous Expression of Full-Length and Truncated Human ZIP4 Zinc Transporter in Saccharomyces cerevisiae

The human (h) transporter hZIP4 is the primary Zn(2+) importer in the intestine. hZIP4 is also expressed in a variety of organs such as the pancreas and brain. Dysfunction of hZIP4 can result in the Zn(2+) deficiency disease acrodermatitis enteropathica (AE). AE can disrupt digestive and immune syst...

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Detalles Bibliográficos
Autores principales: Liu, Yuting, Bafaro, Elizabeth M., Dempski, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138318/
https://www.ncbi.nlm.nih.gov/pubmed/35625653
http://dx.doi.org/10.3390/biom12050726