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Structural Insights into the Intrinsically Disordered GPCR C-Terminal Region, Major Actor in Arrestin-GPCR Interaction

Arrestin-dependent pathways are a central component of G protein-coupled receptor (GPCRs) signaling. However, the molecular processes regulating arrestin binding are to be further illuminated, in particular with regard to the structural impact of GPCR C-terminal disordered regions. Here, we used an...

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Detalles Bibliográficos
Autores principales: Guillien, Myriam, Mouhand, Assia, Fournet, Aurélie, Gontier, Amandine, Martí Navia, Aleix, Cordeiro, Tiago N., Allemand, Frédéric, Thureau, Aurélien, Banères, Jean-Louis, Bernadó, Pau, Sibille, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138321/
https://www.ncbi.nlm.nih.gov/pubmed/35625550
http://dx.doi.org/10.3390/biom12050617