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Comparative Transcriptome Analysis Reveals That Exendin-4 Improves Steatosis in HepG2 Cells by Modulating Signaling Pathways Related to Lipid Metabolism

No therapy exists for non-alcoholic fatty liver disease (NAFLD). However, glucagon-like peptide receptor agonists (GLP-1RAs) showed a beneficial effect on NAFLD, although the underpinning mechanisms remain unclear due to their pleiotropic effects. We examined the implicated signaling pathways using...

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Detalles Bibliográficos
Autores principales: Errafii, Khaoula, Khalifa, Olfa, Al-Akl, Neyla S., Arredouani, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138370/
https://www.ncbi.nlm.nih.gov/pubmed/35625757
http://dx.doi.org/10.3390/biomedicines10051020