The Tarantula Toxin ω-Avsp1a Specifically Inhibits Human Ca(V)3.1 and Ca(V)3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor

Inhibition of T-type calcium channels (Ca(V)3) prevents development of diseases related to cardiovascular and nerve systems. Further, knockout animal studies have revealed that some diseases are mediated by specific subtypes of Ca(V)3. However, subtype-specific Ca(V)3 inhibitors for therapeutic purp...

Descripción completa

Detalles Bibliográficos
Autores principales: Herzig, Volker, Chen, Yong-Cyuan, Chin, Yanni K.-Y., Dekan, Zoltan, Chang, Yu-Wang, Yu, Hui-Ming, Alewood, Paul F., Chen, Chien-Chang, King, Glenn F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138389/
https://www.ncbi.nlm.nih.gov/pubmed/35625803
http://dx.doi.org/10.3390/biomedicines10051066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138389/
https://www.ncbi.nlm.nih.gov/pubmed/35625803
http://dx.doi.org/10.3390/biomedicines10051066

Ejemplares similares