In Silico Integration of Transcriptome and Interactome Predicts an ETP-ALL-Specific Transcriptional Footprint that Decodes its Developmental Propensity

Early T precursor acute lymphoblastic leukemia (ETP-ALL) exhibits poor clinical outcomes and high relapse rates following conventional chemotherapeutic protocols. Extensive developmental flexibility of the multipotent ETP-ALL blasts with considerable intra-population heterogeneity in terms of immuno...

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Detalles Bibliográficos
Autores principales: Mukherjee, Soumyadeep, Kar, Arpita, Paul, Paramita, Dey, Souvik, Biswas, Avik, Barik, Subhasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138408/
https://www.ncbi.nlm.nih.gov/pubmed/35646901
http://dx.doi.org/10.3389/fcell.2022.899752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138408/
https://www.ncbi.nlm.nih.gov/pubmed/35646901
http://dx.doi.org/10.3389/fcell.2022.899752

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