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A New Topical Candidate in Acne Treatment: Characterization of the Meclozine Hydrochloride as an Anti-Inflammatory Compound from In Vitro to a Preliminary Clinical Study

Acne is a chronic inflammatory multifactorial disease involving the anaerobic bacterium Cutibacterium acnes (C. acnes). Current acne treatments are associated with adverse effects, limiting treatment compliance and use. We showed that meclozine, an anti-histaminic H1 compound, has anti-inflammatory...

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Detalles Bibliográficos
Autores principales: Grange, Philippe A., Ollagnier, Guillaume, Beauvais Remigereau, Laurianne, Nicco, Carole, Mayslich, Constance, Marcelin, Anne-Geneviève, Calvez, Vincent, Dupin, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138413/
https://www.ncbi.nlm.nih.gov/pubmed/35625668
http://dx.doi.org/10.3390/biomedicines10050931