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A New Topical Candidate in Acne Treatment: Characterization of the Meclozine Hydrochloride as an Anti-Inflammatory Compound from In Vitro to a Preliminary Clinical Study
Acne is a chronic inflammatory multifactorial disease involving the anaerobic bacterium Cutibacterium acnes (C. acnes). Current acne treatments are associated with adverse effects, limiting treatment compliance and use. We showed that meclozine, an anti-histaminic H1 compound, has anti-inflammatory...
Autores principales: | Grange, Philippe A., Ollagnier, Guillaume, Beauvais Remigereau, Laurianne, Nicco, Carole, Mayslich, Constance, Marcelin, Anne-Geneviève, Calvez, Vincent, Dupin, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138413/ https://www.ncbi.nlm.nih.gov/pubmed/35625668 http://dx.doi.org/10.3390/biomedicines10050931 |
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