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Corticosteroid-Refractory Myositis After Dual BRAF and MEK Inhibition in a Patient with BRAF V600E-Mutant Metastatic Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma is a rare malignancy, which is rich in actionable alterations. Genomic aberrations in the mitogen-activated protein kinase (MAPK) pathway are common, and BRAF exon 15 p.V600E mutations are present in 5–7% of biliary tract cancers (BTC). Dual inhibition of BRAF and MEK...

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Detalles Bibliográficos
Autores principales: DiPeri, Timothy P., Demirhan, Mehmet, Karp, Daniel D., Fu, Siqing, Hong, David S., Subbiah, Vivek, Lim, Joann, Ballester, Leomar Y., Tayar, Jean H., Suarez-Almazor, Maria E., Javle, Milind, Meric-Bernstam, Funda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Innovative Healthcare Institute 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138421/
https://www.ncbi.nlm.nih.gov/pubmed/35663835
http://dx.doi.org/10.36401/JIPO-21-18