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Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra- and Extracellular pH and Internalization Rates

pH-sensitive fluorescent proteins as genetically encoded pH sensors are promising tools for monitoring intra- and extracellular pH. However, there is a lack of ratiometric pH sensors, which offer a good dynamic range and can be purified and applied extracellularly to investigate uptake. In our study...

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Detalles Bibliográficos
Autores principales: Karsten, Lennard, Goett-Zink, Lukas, Schmitz, Julian, Hoffrogge, Raimund, Grünberger, Alexander, Kottke, Tilman, Müller, Kristian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138566/
https://www.ncbi.nlm.nih.gov/pubmed/35624572
http://dx.doi.org/10.3390/bios12050271