GTP-Dependent Regulation of CTP Synthase: Evolving Insights into Allosteric Activation and NH(3) Translocation

Cytidine-5′-triphosphate (CTP) synthase (CTPS) is the class I glutamine-dependent amidotransferase (GAT) that catalyzes the last step in the de novo biosynthesis of CTP. Glutamine hydrolysis is catalyzed in the GAT domain and the liberated ammonia is transferred via an intramolecular tunnel to the s...

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Detalles Bibliográficos
Autores principales: Bearne, Stephen L., Guo, Chen-Jun, Liu, Ji-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138612/
https://www.ncbi.nlm.nih.gov/pubmed/35625575
http://dx.doi.org/10.3390/biom12050647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138612/
https://www.ncbi.nlm.nih.gov/pubmed/35625575
http://dx.doi.org/10.3390/biom12050647

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