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Molecular Signature of Neuroinflammation Induced in Cytokine-Stimulated Human Cortical Spheroids

Crucial in the pathogenesis of neurodegenerative diseases is the process of neuroinflammation that is often linked to the pro-inflammatory cytokines Tumor necrosis factor alpha (TNFα) and Interleukin-1beta (IL-1β). Human cortical spheroids (hCSs) constitute a valuable tool to study the molecular mec...

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Detalles Bibliográficos
Autores principales: De Kleijn, Kim M. A., Straasheijm, Kirsten R., Zuure, Wieteke A., Martens, Gerard J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138619/
https://www.ncbi.nlm.nih.gov/pubmed/35625761
http://dx.doi.org/10.3390/biomedicines10051025