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Probing Structural Perturbation of Biomolecules by Extracting Cryo-EM Data Heterogeneity
Single-particle cryogenic electron microscopy (cryo-EM) has become an indispensable tool to probe high-resolution structural detail of biomolecules. It enables direct visualization of the biomolecules and opens a possibility for averaging molecular images to reconstruct a three-dimensional Coulomb p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138638/ https://www.ncbi.nlm.nih.gov/pubmed/35625556 http://dx.doi.org/10.3390/biom12050628 |