Targeted Inhibition of O-Linked β-N-Acetylglucosamine Transferase as a Promising Therapeutic Strategy to Restore Chemosensitivity and Attenuate Aggressive Tumor Traits in Chemoresistant Urothelial Carcinoma of the Bladder

Acquisition of acquired chemoresistance during treatment cycles in urothelial carcinoma of the bladder (UCB) is the major cause of death through enhancing the risk of cancer progression and metastasis. Elevated glucose flux through the abnormal upregulation of O-linked β-N-acetylglucosamine (O-GlcNA...

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Detalles Bibliográficos
Autores principales: Lee, Hye Won, Kang, Mi Ju, Kwon, Young-Ju, Abdi Nansa, Sama, Jung, Eui Hyun, Kim, Sung Han, Lee, Sang-Jin, Jeong, Kyung-Chae, Kim, Youngwook, Cheong, Heesun, Seo, Ho Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138654/
https://www.ncbi.nlm.nih.gov/pubmed/35625898
http://dx.doi.org/10.3390/biomedicines10051162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138654/
https://www.ncbi.nlm.nih.gov/pubmed/35625898
http://dx.doi.org/10.3390/biomedicines10051162

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