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Targeted Inhibition of O-Linked β-N-Acetylglucosamine Transferase as a Promising Therapeutic Strategy to Restore Chemosensitivity and Attenuate Aggressive Tumor Traits in Chemoresistant Urothelial Carcinoma of the Bladder
Acquisition of acquired chemoresistance during treatment cycles in urothelial carcinoma of the bladder (UCB) is the major cause of death through enhancing the risk of cancer progression and metastasis. Elevated glucose flux through the abnormal upregulation of O-linked β-N-acetylglucosamine (O-GlcNA...
Autores principales: | Lee, Hye Won, Kang, Mi Ju, Kwon, Young-Ju, Abdi Nansa, Sama, Jung, Eui Hyun, Kim, Sung Han, Lee, Sang-Jin, Jeong, Kyung-Chae, Kim, Youngwook, Cheong, Heesun, Seo, Ho Kyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138654/ https://www.ncbi.nlm.nih.gov/pubmed/35625898 http://dx.doi.org/10.3390/biomedicines10051162 |
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