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Scratching the Surface—An Overview of the Roles of Cell Surface GRP78 in Cancer

The 78 kDa glucose-regulated protein (GRP78) is considered an endoplasmic reticulum (ER)-resident molecular chaperone that plays a crucial role in protein folding homeostasis by regulating the unfolded protein response (UPR) and inducing numerous proapoptotic and autophagic pathways within the eukar...

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Detalles Bibliográficos
Autores principales: Chen, Jack, Lynn, Edward G., Yousof, Tamana R., Sharma, Hitesh, MacDonald, Melissa E., Byun, Jae Hyun, Shayegan, Bobby, Austin, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138746/
https://www.ncbi.nlm.nih.gov/pubmed/35625836
http://dx.doi.org/10.3390/biomedicines10051098