Cargando…
Scratching the Surface—An Overview of the Roles of Cell Surface GRP78 in Cancer
The 78 kDa glucose-regulated protein (GRP78) is considered an endoplasmic reticulum (ER)-resident molecular chaperone that plays a crucial role in protein folding homeostasis by regulating the unfolded protein response (UPR) and inducing numerous proapoptotic and autophagic pathways within the eukar...
Autores principales: | Chen, Jack, Lynn, Edward G., Yousof, Tamana R., Sharma, Hitesh, MacDonald, Melissa E., Byun, Jae Hyun, Shayegan, Bobby, Austin, Richard C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138746/ https://www.ncbi.nlm.nih.gov/pubmed/35625836 http://dx.doi.org/10.3390/biomedicines10051098 |
Ejemplares similares
-
The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness
por: Chen, Hsin-Ying, et al.
Publicado: (2018) -
The Cell Surface GRP78 Facilitates the Invasion of Hepatocellular Carcinoma Cells
por: Zhang, Xiu-Xiu, et al.
Publicado: (2013) -
Cell surface GRP78 promotes stemness in normal and neoplastic cells
por: Conner, Clay, et al.
Publicado: (2020) -
Potential to Eradicate Cancer Stemness by Targeting Cell Surface GRP78
por: Chen, Hsin-Ying, et al.
Publicado: (2022) -
Cell surface GRP78 as a biomarker and target for suppressing glioma cells
por: Kang, Bo Ram, et al.
Publicado: (2016)