Extracellular Vesicles from Steatotic Hepatocytes Provoke Pro-Fibrotic Responses in Cultured Stellate Cells

Hepatic steatosis and chronic hepatocyte damage ultimately lead to liver fibrosis. Key pathophysiological steps are the activation and transdifferentiation of hepatic stellate cells. We assessed the interplay between hepatocytes and hepatic stellate cells under normal and steatotic conditions. We hy...

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Detalles Bibliográficos
Autores principales: Koenen, Maria Teresa, Brandt, Elisa Fabiana, Kaczor, Dawid Marcin, Caspers, Tim, Heinzmann, Alexandra Catharina Anna, Fischer, Petra, Heinrichs, Daniel, Wirtz, Theresa Hildegard, Trautwein, Christian, Koenen, Rory R, Berres, Marie-Luise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138794/
https://www.ncbi.nlm.nih.gov/pubmed/35625625
http://dx.doi.org/10.3390/biom12050698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138794/
https://www.ncbi.nlm.nih.gov/pubmed/35625625
http://dx.doi.org/10.3390/biom12050698

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