Targeting TKI-Activated NFKB2-MIF/CXCLs-CXCR2 Signaling Pathways in FLT3 Mutated Acute Myeloid Leukemia Reduced Blast Viability

Disease relapse is a common cause of treatment failure in FMS-like tyrosine kinase 3 (FLT3) mutated acute myeloid leukemia (AML). In this study, to identify therapeutic targets responsible for the survival and proliferation of leukemic cells (blasts) with FLT3 mutations after gilteritinib (GILT, a 2...

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Detalles Bibliográficos
Autores principales: Cao, Huynh, Tadros, Verena, Hiramoto, Benjamin, Leeper, Kevin, Hino, Christopher, Xiao, Jeffrey, Pham, Bryan, Kim, Do Hyun, Reeves, Mark E., Chen, Chien-Shing, Zhong, Jiang F., Zhang, Ke K., Xie, Linglin, Wasnik, Samiksha, Baylink, David J., Xu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138861/
https://www.ncbi.nlm.nih.gov/pubmed/35625776
http://dx.doi.org/10.3390/biomedicines10051038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138861/
https://www.ncbi.nlm.nih.gov/pubmed/35625776
http://dx.doi.org/10.3390/biomedicines10051038

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