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In Vivo Evaluation of Fibroblast Growth Factor Receptor Inhibition in Mouse Xenograft Models of Gastrointestinal Stromal Tumor

Advanced gastrointestinal stromal tumors (GIST) are typically treated with tyrosine kinase inhibitors, and imatinib is the most commonly used standard of care in first line treatments. The use of this and other tyrosine kinase inhibitors is associated with objective tumor responses and prolongation...

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Detalles Bibliográficos
Autores principales: Schöffski, Patrick, Gebreyohannes, Yemarshet, Van Looy, Thomas, Manley, Paul, Growney, Joseph D., Squires, Matthew, Wozniak, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138864/
https://www.ncbi.nlm.nih.gov/pubmed/35625872
http://dx.doi.org/10.3390/biomedicines10051135