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Myeloid-Specific Pyruvate-Kinase-Type-M2-Deficient Mice Are Resistant to Acute Lung Injury

Infiltration of polymorphonuclear neutrophils (PMNs) plays a central role in acute lung injury (ALI). The mechanisms governing PMN inflammatory responses, however, remain incompletely understood. Based on our recent study showing a non-metabolic role of pyruvate kinase type M2 (PKM2) in controlling...

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Detalles Bibliográficos
Autores principales: Sun, Xinlei, Shi, Fujie, Wang, Weiran, Wu, Yunfei, Qu, Shuang, Li, Jing, Liang, Hongwei, Zen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138865/
https://www.ncbi.nlm.nih.gov/pubmed/35625931
http://dx.doi.org/10.3390/biomedicines10051193