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Myeloid-Specific Pyruvate-Kinase-Type-M2-Deficient Mice Are Resistant to Acute Lung Injury
Infiltration of polymorphonuclear neutrophils (PMNs) plays a central role in acute lung injury (ALI). The mechanisms governing PMN inflammatory responses, however, remain incompletely understood. Based on our recent study showing a non-metabolic role of pyruvate kinase type M2 (PKM2) in controlling...
Autores principales: | Sun, Xinlei, Shi, Fujie, Wang, Weiran, Wu, Yunfei, Qu, Shuang, Li, Jing, Liang, Hongwei, Zen, Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138865/ https://www.ncbi.nlm.nih.gov/pubmed/35625931 http://dx.doi.org/10.3390/biomedicines10051193 |
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