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Sustainability of diet-based moderate calorie restriction among obese patients with metabolic-associated fatty liver disease
BACKGROUND AND AIM: The long-term sustainability of weight loss continues to be a subject of investigation. This study was designed to examine the effects of weight loss and the long-term sustainability of lifestyle modifications among obese patients with metabolic-associated fatty liver disease (MA...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kare Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138938/ https://www.ncbi.nlm.nih.gov/pubmed/35784903 http://dx.doi.org/10.14744/hf.2021.2021.0014 |
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author | Guveli, Hakan Ozlu, Tugce Ersoy Tasar, Busra Batuhan Kenger, Emre Kaya, Eda |
author_facet | Guveli, Hakan Ozlu, Tugce Ersoy Tasar, Busra Batuhan Kenger, Emre Kaya, Eda |
author_sort | Guveli, Hakan |
collection | PubMed |
description | BACKGROUND AND AIM: The long-term sustainability of weight loss continues to be a subject of investigation. This study was designed to examine the effects of weight loss and the long-term sustainability of lifestyle modifications among obese patients with metabolic-associated fatty liver disease (MAFLD). MATERIALS AND METHODS: A total of 40 patients who were prescribed a hypocaloric diet (~500 calories reduction for each patient), and who were followed up for 12 weeks in 4 face-to-face interviews were enrolled in the study. The patients were contacted at the 36(th) month, and their current weight was recorded. RESULTS: The mean weight at baseline of 87±13 kg decreased to 79±11 kg after 12 weeks of intervention (p<0.001). The mean weight at the 36(th) month did not significantly differ from that measured at the baseline (p=0.563). The mean controlled attenuation parameter decreased from 320±13 dB/m to 273±37 dB/m (p<0.001), while the median liver stiffness measurement decreased from 8.7 kPa (3.6–45.7 kPa) to 5.7 kPa (2.2–29.9 kPa) (p<0.001). CONCLUSION: Strict follow-up through nutritional consultation can help achieve weight loss in obese patients with MAFLD. However, for long-term results, the collaboration of nutritionists and gastroenterologists is essential to prevent weight regain. |
format | Online Article Text |
id | pubmed-9138938 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Kare Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-91389382022-07-01 Sustainability of diet-based moderate calorie restriction among obese patients with metabolic-associated fatty liver disease Guveli, Hakan Ozlu, Tugce Ersoy Tasar, Busra Batuhan Kenger, Emre Kaya, Eda Hepatol Forum Research Article - Sustainability of diet in fatty liver BACKGROUND AND AIM: The long-term sustainability of weight loss continues to be a subject of investigation. This study was designed to examine the effects of weight loss and the long-term sustainability of lifestyle modifications among obese patients with metabolic-associated fatty liver disease (MAFLD). MATERIALS AND METHODS: A total of 40 patients who were prescribed a hypocaloric diet (~500 calories reduction for each patient), and who were followed up for 12 weeks in 4 face-to-face interviews were enrolled in the study. The patients were contacted at the 36(th) month, and their current weight was recorded. RESULTS: The mean weight at baseline of 87±13 kg decreased to 79±11 kg after 12 weeks of intervention (p<0.001). The mean weight at the 36(th) month did not significantly differ from that measured at the baseline (p=0.563). The mean controlled attenuation parameter decreased from 320±13 dB/m to 273±37 dB/m (p<0.001), while the median liver stiffness measurement decreased from 8.7 kPa (3.6–45.7 kPa) to 5.7 kPa (2.2–29.9 kPa) (p<0.001). CONCLUSION: Strict follow-up through nutritional consultation can help achieve weight loss in obese patients with MAFLD. However, for long-term results, the collaboration of nutritionists and gastroenterologists is essential to prevent weight regain. Kare Publishing 2021-09-15 /pmc/articles/PMC9138938/ /pubmed/35784903 http://dx.doi.org/10.14744/hf.2021.2021.0014 Text en © Copyright 2021 by Hepatology Forum - Available online at www.hepatologyforum.org https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
spellingShingle | Research Article - Sustainability of diet in fatty liver Guveli, Hakan Ozlu, Tugce Ersoy Tasar, Busra Batuhan Kenger, Emre Kaya, Eda Sustainability of diet-based moderate calorie restriction among obese patients with metabolic-associated fatty liver disease |
title | Sustainability of diet-based moderate calorie restriction among obese patients with metabolic-associated fatty liver disease |
title_full | Sustainability of diet-based moderate calorie restriction among obese patients with metabolic-associated fatty liver disease |
title_fullStr | Sustainability of diet-based moderate calorie restriction among obese patients with metabolic-associated fatty liver disease |
title_full_unstemmed | Sustainability of diet-based moderate calorie restriction among obese patients with metabolic-associated fatty liver disease |
title_short | Sustainability of diet-based moderate calorie restriction among obese patients with metabolic-associated fatty liver disease |
title_sort | sustainability of diet-based moderate calorie restriction among obese patients with metabolic-associated fatty liver disease |
topic | Research Article - Sustainability of diet in fatty liver |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138938/ https://www.ncbi.nlm.nih.gov/pubmed/35784903 http://dx.doi.org/10.14744/hf.2021.2021.0014 |
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