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Natural Polyphenols, 1,2,3,4,6-O-Pentagalloyglucose and Proanthocyanidins, as Broad-Spectrum Anticoronaviral Inhibitors Targeting Mpro and RdRp of SARS-CoV-2

The natural plant dietary polyphenols 1,2,3,4,6-O-Pentagalloylglucose (PGG) and proanthocyanidin (PAC) have potent antioxidant activity and a variety of pharmacological activities, including antiviral activity. In this study, we examined the inhibitory effect of PGG and PAC on SARS-CoV-2 virus infec...

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Detalles Bibliográficos
Autores principales: Jin, Young-Hee, Lee, Jihye, Jeon, Sangeun, Kim, Seungtaek, Min, Jung Sun, Kwon, Sunoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138959/
https://www.ncbi.nlm.nih.gov/pubmed/35625907
http://dx.doi.org/10.3390/biomedicines10051170