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Ziprasidone Induces Rabbit Atrium Arrhythmogenesis via Modification of Oxidative Stress and Sodium/Calcium Homeostasis

Background: Atypical antipsychotics increase the risk of atrial arrhythmias and sudden cardiac death. This study investigated whether ziprasidone, a second-generation antipsychotic, affected intracellular Ca(2+) and Na(+) regulation and oxidative stress, providing proarrhythmogenic substrates in atr...

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Detalles Bibliográficos
Autores principales: Tai, Buh-Yuan, Lu, Ming-Kun, Yang, Hsiang-Yu, Tsai, Chien-Sung, Lin, Chih-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138982/
https://www.ncbi.nlm.nih.gov/pubmed/35625713
http://dx.doi.org/10.3390/biomedicines10050976