The Novel Pimavanserin Derivative ST-2300 with Histamine H(3) Receptor Affinity Shows Reduced 5-HT(2A) Binding, but Maintains Antidepressant- and Anxiolytic-like Properties in Mice

The therapy of depression is challenging and still unsatisfactory despite the presence of many antidepressant drugs on the market. Consequently, there is a continuous need to search for new, safer, and more effective antidepressant therapeutics. Previous studies have suggested a potential associatio...

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Detalles Bibliográficos
Autores principales: Venkatachalam, Karthikkumar, Zhong, Sicheng, Dubiel, Mariam, Satała, Grzegorz, Sadek, Bassem, Stark, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138994/
https://www.ncbi.nlm.nih.gov/pubmed/35625611
http://dx.doi.org/10.3390/biom12050683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138994/
https://www.ncbi.nlm.nih.gov/pubmed/35625611
http://dx.doi.org/10.3390/biom12050683

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