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The Novel Pimavanserin Derivative ST-2300 with Histamine H(3) Receptor Affinity Shows Reduced 5-HT(2A) Binding, but Maintains Antidepressant- and Anxiolytic-like Properties in Mice
The therapy of depression is challenging and still unsatisfactory despite the presence of many antidepressant drugs on the market. Consequently, there is a continuous need to search for new, safer, and more effective antidepressant therapeutics. Previous studies have suggested a potential associatio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9138994/ https://www.ncbi.nlm.nih.gov/pubmed/35625611 http://dx.doi.org/10.3390/biom12050683 |