Insights into a Cancer-Target Demethylase: Substrate Prediction through Systematic Specificity Analysis for KDM3A

Jumonji C (JmjC) lysine demethylases (KDMs) catalyze the removal of methyl (-CH(3)) groups from modified lysyl residues. Several JmjC KDMs promote cancerous properties and these findings have primarily been in relation to histone demethylation. However, the biological roles of these enzymes are incr...

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Detalles Bibliográficos
Autores principales: Chopra, Anand, Willmore, William G., Biggar, Kyle K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139010/
https://www.ncbi.nlm.nih.gov/pubmed/35625569
http://dx.doi.org/10.3390/biom12050641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139010/
https://www.ncbi.nlm.nih.gov/pubmed/35625569
http://dx.doi.org/10.3390/biom12050641

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