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The Actin-Binding Protein Cortactin Promotes Sepsis Severity by Supporting Excessive Neutrophil Infiltration into the Lung

Sepsis is a systemic infection that can lead to multi-organ failure. It is characterised by an uncontrolled immune response with massive neutrophil influx into peripheral organs. Neutrophil extravasation into tissues depends on actin remodeling and actin-binding proteins such as cortactin, which is...

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Detalles Bibliográficos
Autores principales: Lartey, Nathaniel L., Vargas-Robles, Hilda, Guerrero-Fonseca, Idaira M., García-Ponce, Alexander, Salinas-Lara, Citlaltepetl, Rottner, Klemens, Schnoor, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139066/
https://www.ncbi.nlm.nih.gov/pubmed/35625756
http://dx.doi.org/10.3390/biomedicines10051019