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IFNγ-Treated Macrophages Induce EMT through the WNT Pathway: Relevance in Crohn’s Disease

Background: Fibrosis is a common complication of Crohn’s disease (CD) in which macrophages play a central role. Epithelial-mesenchymal transition (EMT) and the WNT pathway have been associated with fibrosis. We aim to analyse the relevance of the tissue microenvironment in macrophage phenotype and t...

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Detalles Bibliográficos
Autores principales: Macias-Ceja, Dulce C., Coll, Sandra, Bauset, Cristina, Seco-Cervera, Marta, Gisbert-Ferrándiz, Laura, Navarro, Francisco, Cosin-Roger, Jesus, Calatayud, Sara, Barrachina, María D., Ortiz-Masia, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139093/
https://www.ncbi.nlm.nih.gov/pubmed/35625832
http://dx.doi.org/10.3390/biomedicines10051093