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Gene Polymorphism of Biotransformation Enzymes and Ciprofloxacin Pharmacokinetics in Pediatric Patients with Cystic Fibrosis

(1) Background: Ciprofloxacin (CPF) is widely used for the treatment of cystic fibrosis, including pediatric patients, but its pharmacokinetics is poorly studied in this population. Optimal CPF dosing in pediatric patients may be affected by gene polymorphism of the enzymes involved in its biotransf...

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Detalles Bibliográficos
Autores principales: Zyryanov, Sergey K., Ushkalova, Elena A., Kondratyeva, Elena I., Butranova, Olga I., Kondakova, Yulia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139162/
https://www.ncbi.nlm.nih.gov/pubmed/35625789
http://dx.doi.org/10.3390/biomedicines10051050