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Rational Discovery of Antiviral Whey Protein-Derived Small Peptides Targeting the SARS-CoV-2 Main Protease

In the present work, and for the first time, three whey protein-derived peptides (IAEK, IPAVF, MHI), endowed with ACE inhibitory activity, were examined for their antiviral activity against the SARS-CoV-2 3C-like protease (3CL(pro)) and Human Rhinovirus 3C protease (3C(pro)) by employing molecular d...

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Detalles Bibliográficos
Autores principales: Gambacorta, Nicola, Caputo, Leonardo, Quintieri, Laura, Monaci, Linda, Ciriaco, Fulvio, Nicolotti, Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139167/
https://www.ncbi.nlm.nih.gov/pubmed/35625804
http://dx.doi.org/10.3390/biomedicines10051067