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Rabphilin-3A Drives Structural Modifications of Dendritic Spines Induced by Long-Term Potentiation

The interaction of Rabphilin-3A (Rph3A) with the NMDA receptor (NMDAR) in hippocampal neurons plays a pivotal role in the synaptic retention of this receptor. The formation of a Rph3A/NMDAR complex is needed for the induction of long-term potentiation and NMDAR-dependent hippocampal behaviors, such...

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Detalles Bibliográficos
Autores principales: Franchini, Luca, Stanic, Jennifer, Barzasi, Marta, Zianni, Elisa, Mauceri, Daniela, Diluca, Monica, Gardoni, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139176/
https://www.ncbi.nlm.nih.gov/pubmed/35626653
http://dx.doi.org/10.3390/cells11101616