Aneurysm-on-a-Chip: Setting Flow Parameters for Microfluidic Endothelial Cultures Based on Computational Fluid Dynamics Modeling of Intracranial Aneurysms

Intracranial aneurysms are pouch-like extrusions from the vessels at the base of the brain which can rupture and cause a subarachnoid hemorrhage. The pathophysiological mechanism of aneurysm formation is thought to be a consequence of blood flow (hemodynamic) induced changes on the endothelium. In t...

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Detalles Bibliográficos
Autores principales: Vivas, Aisen, Mikhal, Julia, Ong, Gabriela M., Eigenbrodt, Anna, van der Meer, Andries D., Aquarius, Rene, Geurts, Bernard J., Boogaarts, Hieronymus D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139202/
https://www.ncbi.nlm.nih.gov/pubmed/35624990
http://dx.doi.org/10.3390/brainsci12050603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139202/
https://www.ncbi.nlm.nih.gov/pubmed/35624990
http://dx.doi.org/10.3390/brainsci12050603

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