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Activation of MT1/MT2 to Protect Testes and Leydig Cells against Cisplatin-Induced Oxidative Stress through the SIRT1/Nrf2 Signaling Pathway

There is growing concern that chemotherapy drugs can damage Leydig cells and inhibit the production of testosterone. Increasing evidence shows that melatonin benefits the reproductive process. This study mainly explores the protective effect and possible molecular mechanism of melatonin regarding ci...

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Detalles Bibliográficos
Autores principales: Zhang, Junqiang, Fang, Yuan, Tang, Dongdong, Xu, Xingyu, Zhu, Xiaoqian, Wu, Shusheng, Yu, Hui, Cheng, Huiru, Luo, Ting, Shen, Qunshan, Gao, Yang, Ma, Cong, Liu, Yajing, Wei, Zhaolian, Chen, Xiaoyu, Tao, Fangbiao, He, Xiaojin, Cao, Yunxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139217/
https://www.ncbi.nlm.nih.gov/pubmed/35626727
http://dx.doi.org/10.3390/cells11101690