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Characterization of Peripheral Blood TCR in Patients with Type 1 Diabetes Mellitus by BD Rhapsody(TM) VDJ CDR3 Assay

The sequence of complementarity-determining region 3 of the T-cell receptor (TCR) varies widely due to the insertion of random bases during V-(D)-J recombination. In this study, we used single-cell VDJ sequencing using the latest technology, BD Rhapsody, to identify the TCR sequences of autoreactive...

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Detalles Bibliográficos
Autores principales: Okamura, Takuro, Hamaguchi, Masahide, Tominaga, Hiroyuki, Kitagawa, Noriyuki, Hashimoto, Yoshitaka, Majima, Saori, Senmaru, Takafumi, Okada, Hiroshi, Ushigome, Emi, Nakanishi, Naoko, Shichino, Shigeyuki, Fukui, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139223/
https://www.ncbi.nlm.nih.gov/pubmed/35626661
http://dx.doi.org/10.3390/cells11101623