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Is L-Glutamate Toxic to Neurons and Thereby Contributes to Neuronal Loss and Neurodegeneration? A Systematic Review

L-glutamate (L-Glu) is a nonessential amino acid, but an extensively utilised excitatory neurotransmitter with critical roles in normal brain function. Aberrant accumulation of L-Glu has been linked to neurotoxicity and neurodegeneration. To investigate this further, we systematically reviewed the l...

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Detalles Bibliográficos
Autores principales: AL-Nasser, Maryam N., Mellor, Ian R., Carter, Wayne G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139234/
https://www.ncbi.nlm.nih.gov/pubmed/35624964
http://dx.doi.org/10.3390/brainsci12050577