Whole-Genome Sequencing Identifies PPARGC1A as a Putative Modifier of Cancer Risk in BRCA1/2 Mutation Carriers

SIMPLE SUMMARY: In search of genetic factors that affect cancer risks in BRCA carriers, we carried out the first whole-genome sequencing study in a unique registry of familial ovarian cancer, selected to enrich with BRCA1/2 carriers. We are the first to survey rare variants, particularly the non-cod...

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Detalles Bibliográficos
Autores principales: Zhu, Qianqian, Wang, Jie, Yu, Han, Hu, Qiang, Bateman, Nicholas W., Long, Mark, Rosario, Spencer, Schultz, Emily, Dalgard, Clifton L., Wilkerson, Matthew D., Sukumar, Gauthaman, Huang, Ruea-Yea, Kaur, Jasmine, Lele, Shashikant B., Zsiros, Emese, Villella, Jeannine, Lugade, Amit, Moysich, Kirsten, Conrads, Thomas P., Maxwell, George L., Odunsi, Kunle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139302/
https://www.ncbi.nlm.nih.gov/pubmed/35625955
http://dx.doi.org/10.3390/cancers14102350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139302/
https://www.ncbi.nlm.nih.gov/pubmed/35625955
http://dx.doi.org/10.3390/cancers14102350

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