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Identification of the Transcriptional Biomarkers Panel Linked to Pathological Remodelling of the Eye Tissues in Various HD Mouse Models

Ocular abnormalities are becoming associated with a spectrum of pathological events in various neurodegenerative diseases. Huntington’s disease (HD) is just such an example of a fatal neurological disorder, where mutated genes (CAG trinucleotide expansions in the Huntingtin gene) have widespread exp...

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Detalles Bibliográficos
Autores principales: Mazur-Michałek, Iwona, Ruciński, Marcin, Sowiński, Mateusz, Pietras, Paulina, Leśniczak-Staszak, Marta, Szaflarski, Witold, Isalan, Mark, Mielcarek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139483/
https://www.ncbi.nlm.nih.gov/pubmed/35626712
http://dx.doi.org/10.3390/cells11101675