Safety and Efficacy of Crizotinib in Combination with Temozolomide and Radiotherapy in Patients with Newly Diagnosed Glioblastoma: Phase Ib GEINO 1402 Trial

SIMPLE SUMMARY: Most patients with glioblastoma, the most frequent primary brain tumor in adults, develop resistance to standard first-line treatment combining temozolomide and radiotherapy. Signaling through the hepatocyte growth factor receptor (c-MET) and the midkine (ALK ligand) promotes gliomag...

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Detalles Bibliográficos
Autores principales: Martínez-García, María, Velasco, Guillermo, Pineda, Estela, Gil-Gil, Miguel, Alameda, Francesc, Capellades, Jaume, Martín-Soberón, Mari Cruz, López-Valero, Israel, Tovar Ambel, Elena, Foro, Palmira, Taus, Álvaro, Arumi, Montserrat, Hernández-Laín, Aurelio, Sepúlveda-Sánchez, Juan Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139576/
https://www.ncbi.nlm.nih.gov/pubmed/35625997
http://dx.doi.org/10.3390/cancers14102393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139576/
https://www.ncbi.nlm.nih.gov/pubmed/35625997
http://dx.doi.org/10.3390/cancers14102393

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